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"Spedia-NMR gave us rapid and efficient access to the concentration profiles of feed components and metabolites to fine-tune our cell culture process." Bram Bout, CTO at Profibrix

  "Spinnovation collaborated with Merck Sharp & Dohme on the development of NMR assays for biologics."             

Merck Sharp & Dohme

  "The Spedia-NMR™ service brings new insights into our cell lines metabolism which enables us to further optimize its performance." Vivalis.              

Call Us: +31-24-240-3400

Email: info@spinnovation-biologics.com

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Spent Media Analysis With Spedia-NMR™_old

We can measure over 40 components at a time, such as feed components (e.g. amino acids, glucose), contaminants and metabolites.

spent-media-analysis4Spedia-NMR™ performs high throughput analyses of cell culture media batches and fed-batches in a very cost-efficient manner, using automated sample analysis and data processing. It outperforms common biochemical (Nova Bioprofile) and HPLC methods in terms of speed, data variability and cost.

We can deliver quantitative data or culture profiling to defined and non-defined media, and our methods are directly in line with FDA Quality by Design policies. We also offer analysis of water-soluble vitamins by LC-MS.

Get a quote for your spent media analysis here.

Receive quantitative or culture profile trend data on these media analytes:

Amino Acids

Alanine
Arginine
Aspactic acid
Asparagine
Cystein
Cystine
Glutamic acid
Glutamine
Glycine
Histidine
Hydroxyproline
Isoleucine
Methionine
Leucine
Lysine
Phenylalanine
Proline
Serine
Threonine
Tryptophane
Tyrosine
Valine

Saccharides

Fucose
Galactose
Glucose
Glucose-1-phosphate
Lactose
Mannose
Raffinose
Sucrose
Xylose

Other Analytes

Acetic Acid
Acetone
Adenine
Adenosine
Butyric acid
Citric acid
Cytidine
Cytosine
Ethanol
Formaldehyde
Formic acid
Fumaric acid
Guanine
Guanosine
2-Hydroxybutyric acid
3-Hydroxybutyric acid
Lactic acid
Maleic acid
Methanol
Propionic acid
Pyruvic acid
Succinic acid
Tris buffer

*Vitamins

Aminobenzaldehyde
Biotin
Choline
Cobalamine
Folic acid
Nicotinamide
Niacin
Pantothenic acid
Pyridoxal
Pyridoxine
Riboflavine
Thiamine

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